Cutaneous vasculitis in children: A nationwide epidemiological

Cutaneous vasculitis (CV) are a complex group of conditions in Background children, of which IgA vasculitis (IgAV) is the most common. The objectives of the current study are to describe the incidence of CV in Spain and to analyze the temporal trend in the last 11 years, as well as it seasonal distribution. Hospital discharges of patients aged 0-18 years with a diagnosis Methods: consistent with CV in Spain from 2005 to 2015 were collected from the Spanish National Institute of Statistics (INE) databases. : A total of 7304 patients from January 2005 to December 2015 were Results included; 6991 patients (95%) had a diagnosis of IgAV. The yearly incidence in the whole group was 7.7 per 100,000. Mean age at diagnoses was 6±3 years and 52% were male. The highest rate of admissions was found in the 5-9 year-old group, followed by those with 0-4 years of age (15.7 and 9.0 admissions per 100.000, respectively). Admissions due to CV followed an annual cyclic pattern, with the highest number of daily admissions during fall and winter months and the lowest number in summer months. There was an overall downwards trend of the number of hospital admissions during the period of study, in both males and females (p=0.01). : We have estimated an incidence of a 7.7 cases per 100,000 CV Conclusions in children in Spain. CV-related hospitalization rates have a marked seasonal pattern, with a peak in fall and winter and a nadir in summer months. Children between 5 and 9 years of age are most frequently affected. There is a decreasing trend in CV-related hospitalization, the causes of which should be further assessed. Leyre Riancho-Zarrabeitia ( ) Corresponding author: [email protected] : Conceptualization, Data Curation, Formal Analysis, Investigation, Methodology, Project Administration, Author roles: Riancho-Zarrabeitia L Software, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing; : Conceptualization, Data Santurtún A Curation, Formal Analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Competing interests: No competing interests were disclosed. Riancho-Zarrabeitia L and Santurtún A. How to cite this article: Cutaneous vasculitis in children: A nationwide epidemiological study in 2017, :1527 (doi: ) Spain [version 1; referees: awaiting peer review] F1000Research 6 10.12688/f1000research.12372.1 © 2017 Riancho-Zarrabeitia L and Santurtún A. This is an open access article distributed under the terms of the Copyright: Creative Commons , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Attribution Licence The author(s) declared that no grants were involved in supporting this work. Grant information: 21 Aug 2017, :1527 (doi: ) First published: 6 10.12688/f1000research.12372.1 1